產(chǎn)品詳情
簡單介紹:
2'-Deoxy-6-thioguanosine
詳情介紹:
Purpose | An anticancer agent |
Characteristics | 6-Thio-dG induces telomere dysfunction in telomerase-positive human cancer cells and hTERT-expressing human fubroblasts, but not in telomerase-negative cells. Treatment with 6-thio-dG results in rapid cell death for a wide variety of cancer cells, whereas normal human fibroblasts and human colonic epithelial cells are mostly unaffected. |
Purity | ≥ 97?% by HPLC |
Chemical Name | 2'-Deoxy-6-thio-D-guanosine;6-Thio-2'-deoxyguanosine; 6-thio-DG |
Formula | C??H??N?O?S |
Permeability | Cell-permeable |
Solubility | DMSO:H?O (1:2) (50 mM) |
Molecular Weight | 283.31 g/mol |
CAS-No | 789-61-7 |
Restrictions | For Research Use only |
Format | Solid |
Handling Advice | Protect from air and moisture |
Storage | -20 °C |
Expiry Date | 36 months |